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Alveolar macrophages also express PD-L1 [106, 111, 113]

PD-L1 draws much attention as an immune checkpoint for improving cancer management [87]

Hattingen et al., 2009)

Regulating lipid production, transportation and decomposition functions with drugs to improve lipid metabolism disorders, especially fatty acid metabolism disorders, and regulating renal energy metabolism can be used as effective methods to prevent and treat RF and delay the progression of CKD [27], which has attracted extensive attention in recent years

This conjugation process transforms lipophilic toxins into water-soluble glutathione adducts that can be efficiently eliminated through bile or urine